Application
A. Western blot analysis on MCF-7 cell lysate using anti-EMSY RabMAb (Cat. #AJ1258a), dilution 1:1,000.Application
B. Immunofluorescent staining of MCF-7 cells using anti-EMSY RabMAb (Cat. #AJ1258a).| Product Name | EMSY Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EMSY, C11orf30, Protein EMSY |
| Clonality | Monoclonal |
|---|---|
| Clone Number | Y474 |
| Host Species | Rabbit |
| Tested Applications | WBIF |
| WB:1:2000~5000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C11orf30 |
|---|---|
| Alternative Names | EMSY C11orf30 Protein EMSY |
| Molecular Weight(MW) | 141468 Da |
| Function | Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2 |
| Tissue Specificity | A synthetic peptide corresponding to residues near the C-term of human EMSY isoform 1 was used as immunogen. |
| Cellular Localization | Nucleus. Note=Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process |
| Entrez Gene | 56946 |
|---|
Application
A. Western blot analysis on MCF-7 cell lysate using anti-EMSY RabMAb (Cat. #AJ1258a), dilution 1:1,000.
Application
B. Immunofluorescent staining of MCF-7 cells using anti-EMSY RabMAb (Cat. #AJ1258a).| Application Notes | WB:1:2000~5000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
