Application
Western blot analysis of CALHM1/FAM26C antibody (N-term) (Cat.# AP7399a) in 293 cell line lysates (35ug/lane). CALHM1 (arrow) was detected using the purified Pab.Application
CALHM1/FAM26C Antibody (N-term) (RB18844) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CALHM1/FAM26C Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
CALHM1/FAM26C Antibody (N-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | CALHM1/FAM26C Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CALHM1; FAM26C; Calcium homeostasis modulator protein 1; Protein FAM26C |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FAM26C |
|---|---|
| Alternative Names | CALHM1 FAM26C Calcium homeostasis modulator protein 1 Protein FAM26C |
| Molecular Weight(MW) | 38264 Da |
| Function | May be a pore-forming ion channel. Controls cytosolic Ca(2+) permeability and cytosolic Ca(2+) concentration. Controls amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca(2+) dependent manner |
| Tissue Specificity | Predominantly expressed in adult brain. Detected also in retinoic acid-differentiated SH-SY5Y cells |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein Note=Colocalizes with HSPA5 at the endoplasmic reticulum |
| Entrez Gene | 255022 |
|---|
Application
Western blot analysis of CALHM1/FAM26C antibody (N-term) (Cat.# AP7399a) in 293 cell line lysates (35ug/lane). CALHM1 (arrow) was detected using the purified Pab.
Application
CALHM1/FAM26C Antibody (N-term) (RB18844) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CALHM1/FAM26C Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
CALHM1/FAM26C Antibody (N-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
