Application
Western blot analysis of CALHM1/FAM26C antibody (Center) (Cat.# AP7399c) in 293 cell line lysates (35ug/lane). CALHM1 (arrow) was detected using the purified Pab.Application
CALHM1/FAM26C Antibody (Center) (RB18845) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CALHM1/FAM26C Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | CALHM1/FAM26C Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CALHM1; FAM26C; Calcium homeostasis modulator protein 1; Protein FAM26C |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FAM26C |
|---|---|
| Alternative Names | CALHM1 FAM26C Calcium homeostasis modulator protein 1 Protein FAM26C |
| Molecular Weight(MW) | 38264 Da |
| Function | May be a pore-forming ion channel. Controls cytosolic Ca(2+) permeability and cytosolic Ca(2+) concentration. Controls amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca(2+) dependent manner |
| Tissue Specificity | Predominantly expressed in adult brain. Detected also in retinoic acid-differentiated SH-SY5Y cells |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein Note=Colocalizes with HSPA5 at the endoplasmic reticulum |
| Entrez Gene | 255022 |
|---|
Application
Western blot analysis of CALHM1/FAM26C antibody (Center) (Cat.# AP7399c) in 293 cell line lysates (35ug/lane). CALHM1 (arrow) was detected using the purified Pab.
Application
CALHM1/FAM26C Antibody (Center) (RB18845) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CALHM1/FAM26C Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
