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CAMK2G (CAMK2 gamma) Antibody (C-term)

Catalog Number:OM228619
OM228619
Discount Price
OM228619-100ul
1~2 Week
100ul
OM228619-50ul
50ul
OM228619-20ul
20ul
1~2 Week
Product Profile
Product Name CAMK2G (CAMK2 gamma) Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias CAMK2G; CAMK; CAMK-II; CAMKG; Calcium/calmodulin-dependent protein kinase type II subunit gamma
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms CAMK
CAMK-II
CAMKG
Alternative Names CAMK2G
CAMK
CAMK-II
CAMKG
Calcium/calmodulin-dependent protein kinase type II subunit gamma
Molecular Weight(MW) 62609 Da
Function Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow- twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning
Tissue Specificity Expressed in skeletal muscle.
Cellular Localization Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (Probable)
Database Links
Entrez Gene 818
Nucleotide Accession O15378
Application

Application

The anti-CAMK2 gamma C-term Pab is used in Western blot to detect CAMK2 gamma in mouse heart tissue lysate.

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Application

Western blot analysis of anti-CAMK2 delta-like Antibody (C-term) in Jurkat cell line lysates (35ug/lane). CAMK2G (arrow) was detected using the purified Pab.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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