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Caspase-6 Antibody (C-term)

Catalog Number:OM228754
OM228754
Discount Price
OM228754-100ul
1~2 Week
100ul
OM228754-50ul
50ul
OM228754-20ul
20ul
1~2 Week
Product Profile
Product Name Caspase-6 Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias CASP6, MCH2, Caspase-6 subunit p11, Apoptotic protease Mch-2
Key Feature
Clonality Monoclonal
Clone Number E180
Host Species Rabbit
Tested Applications WBIHCIF
WB:1:1000~2000 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms MCH2
Alternative Names CASP6
MCH2
Caspase-6 subunit p11
Apoptotic protease Mch-2
Molecular Weight(MW) 33310 Da
Function Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death
Tissue Specificity A synthetic peptide corresponding to residues in C-terminus of human Caspase-6 was used as immunogen. The antibody should recognize both pro-form and p11 subunit.
Cellular Localization Cytoplasm.
Database Links
Entrez Gene 839
Application

Application

A. Western blot analysis on Jurkat cell lysate using anti- Caspase-6 RabMAb (Cat. #AJ1133a); dilution 1:1,000. Cells were (A) untreated and (B) treated with Camptothecin.

Application

B. Immunohistochemical analysis of paraffin-embedded human lung adenocarcinoma using anti-Caspase-6 RabMAb (Cat. #AJ1133a).

Application

C. Immunofluorescent staining of HeLa cells using anti-Caspase-6 RabMAb (Cat. #AJ1133a).
Application Notes WB:1:1000~2000 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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