Application
A. Western blot analysis on Jurkat cell lysate using anti-Pro-Caspase-7 RabMAb (Cat. #AJ1134b), 1:1,000 dilution.Application
B. Immunohistochemical analysis of paraffin-embedded human lung squamous carcinoma using anti- anti-Pro-Caspase-7 RabMAb (Cat. #AJ1134b).| Product Name | Caspase-7 Antibody (Pro) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CASP7, MCH3, Caspase-7 subunit p11, Apoptotic protease Mch-3;CMH-1 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | Y33 |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MCH3 |
|---|---|
| Alternative Names | CASP7 MCH3 Caspase-7 subunit p11 Apoptotic protease Mch-3 CMH-1 |
| Molecular Weight(MW) | 34277 Da |
| Function | Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly- 217' bond. Overexpression promotes programmed cell death |
| Tissue Specificity | Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 840 |
|---|
Application
A. Western blot analysis on Jurkat cell lysate using anti-Pro-Caspase-7 RabMAb (Cat. #AJ1134b), 1:1,000 dilution.
Application
B. Immunohistochemical analysis of paraffin-embedded human lung squamous carcinoma using anti- anti-Pro-Caspase-7 RabMAb (Cat. #AJ1134b).| Application Notes | WB:1:1000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
