Application
A.Western blot analysis on (A) MCF-7 (B) A431 and (C) SKBR3 cell lysates using anti-Cathepsin D RabMAb (Cat. #AJ1139c), dilution 1:5000.Application
B. Paraffin-embedded human breast ductall infiltrating carcinoma tissue stained with anti-Cathepsin D RabMAb. Note positive staining of tumor cells (Cat. #AJ1139c).| Product Name | Cathepsin D Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CTSD, CPSD, Cathepsin D heavy chain |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR3054 |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:20000~50000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CPSD |
|---|---|
| Alternative Names | CTSD CPSD Cathepsin D heavy chain |
| Molecular Weight(MW) | 44552 Da |
| Function | Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease |
| Tissue Specificity | Expressed in the aorta extrcellular space (at protein level) |
| Cellular Localization | Lysosome. Melanosome. Secreted, extracellular space. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380) |
| Entrez Gene | 1509 |
|---|
Application
A.Western blot analysis on (A) MCF-7 (B) A431 and (C) SKBR3 cell lysates using anti-Cathepsin D RabMAb (Cat. #AJ1139c), dilution 1:5000.
Application
B. Paraffin-embedded human breast ductall infiltrating carcinoma tissue stained with anti-Cathepsin D RabMAb. Note positive staining of tumor cells (Cat. #AJ1139c).| Application Notes | WB:1:20000~50000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
