CTSD; CPSD; Cathepsin D; Cathepsin D light chain; Cathepsin D heavy chain
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:50~100
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CPSD
Alternative Names
CTSD CPSD Cathepsin D Cathepsin D light chain Cathepsin D heavy chain
Molecular Weight(MW)
44552 Da
Function
Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease
Tissue Specificity
Expressed in the aorta extrcellular space (at protein level)
Cellular Localization
Lysosome. Melanosome. Secreted, extracellular space. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380)
Western blot analysis of CTSD Antibody (C-term) in A375, MDA-MB231 cell line lysates (35ug/lane). CTSD (arrow) was detected using the purified Pab.
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.