WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
MAL
Alternative Names
CD8 MAL p32 Leu2 CD8A
Molecular Weight(MW)
25729 Da
Function
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains
Cellular Localization
Isoform 1: Cell membrane; Single-pass type I membrane protein