A. Western blot analysis on Raji cell lysates using anti-Phospho-Cdc6 (pS106) RabMAb (Cat. #AJ1176a), 1:2000 dilution. Cells were either (A) untreated (B) treated with FBS
CDC6, CDC18L, Cell division control protein 6 homolog, CDC6-related protein;p62(cdc6)
Modification
p-S106
Key Feature
Clonality
Monoclonal
Clone Number
EPR761(2)
Host Species
Rabbit
Tested Applications
WB
WB:1:1000~2000
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CDC18L
Alternative Names
CDC6 CDC18L Cell division control protein 6 homolog CDC6-related protein p62(cdc6)
Molecular Weight(MW)
62720 Da
Function
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated
Tissue Specificity
A phospho-specific peptide corresponding to residues surrounding Serine 106 of human Cdc6 was used as an immunogen. The antibody only detects Cdc6 phosphorylated on Serine 106.
Cellular Localization
Nucleus. Cytoplasm. Note=The protein is nuclear in G1 and cytoplasmic in S-phase cells
A. Western blot analysis on Raji cell lysates using anti-Phospho-Cdc6 (pS106) RabMAb (Cat. #AJ1176a), 1:2000 dilution. Cells were either (A) untreated (B) treated with FBS
Application Notes
WB:1:1000~2000
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.