Application
CDCA8 (Cat. #AM1868a) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CDCA8 antibody detected the CDCA8 protein (arrow).(1:8000)| Product Name | CDCA8 Antibody (Ascites) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDCA8; PESCRG3; Borealin; Dasra-B; Cell division cycle-associated protein 8; Pluripotent embryonic stem cell-related gene 3 protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 181CT41.2.3 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:2000~16000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PESCRG3 |
|---|---|
| Alternative Names | CDCA8 PESCRG3 Borealin Dasra-B Cell division cycle-associated protein 8 Pluripotent embryonic stem cell-related gene 3 protein |
| Molecular Weight(MW) | 31323 Da |
| Function | Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment |
| Tissue Specificity | This CDCA8 Monoclonal antibody was raised using purified His-tagged recombinant human CDCA8. |
| Cellular Localization | Nucleus, nucleolus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with SENP3 in the nucleolus in interphase cells |
| Entrez Gene | 55143 |
|---|---|
| Nucleotide Accession | NP_060571.1 |
Application
CDCA8 (Cat. #AM1868a) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CDCA8 antibody detected the CDCA8 protein (arrow).(1:8000)| Application Notes | WB:1:2000~16000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
