Application
CDK5RAP2 Antibody (Cat. #AM2155a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CDK5RAP2 antibody detected the CDK5RAP2 protein (arrow).| Product Name | CDK5RAP2 Antibody (Ascites) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDK5RAP2; CEP215; KIAA1633; CDK5 regulatory subunit-associated protein 2; CDK5 activator-binding protein C48; Centrosome-associated protein 215 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Clone Number | 527CT22.9.2 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500~2000" |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CEP215 KIAA1633 |
|---|---|
| Alternative Names | CDK5RAP2 CEP215 KIAA1633 CDK5 regulatory subunit-associated protein 2 CDK5 activator-binding protein C48 Centrosome-associated protein 215 |
| Molecular Weight(MW) | 215038 Da |
| Function | Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion Involved in regulation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Together with MAPRE1, it may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends |
| Tissue Specificity | Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas |
| Cellular Localization | Cytoplasm, cytoskeleton, centrosome. Golgi apparatus. Cytoplasm. Note=Found in the pericentriolar region adhering to the surface of the centrosome and in the region of the centrosomal appendages. Localizes to microtubule plus ends |
| Entrez Gene | 55755 |
|---|---|
| Nucleotide Accession | NP_001011649.1 |
Application
CDK5RAP2 Antibody (Cat. #AM2155a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CDK5RAP2 antibody detected the CDK5RAP2 protein (arrow).| Application Notes | WB:1:500~2000" |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
