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CES2 Antibody (Center)

Catalog Number:OM229623
OM229623
Discount Price
OM229623-100ul
1~2 Week
100ul
OM229623-50ul
50ul
OM229623-20ul
20ul
1~2 Week
Product Profile
Product Name CES2 Antibody (Center)
Antibody Type Primary Antibodies
Antigen Alias CES2; ICE; Cocaine esterase; Carboxylesterase 2; Methylumbelliferyl-acetate deacetylase 2
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms ICE
Alternative Names CES2
ICE
Cocaine esterase
Carboxylesterase 2
Methylumbelliferyl-acetate deacetylase 2
Molecular Weight(MW) 61807 Da
Function Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine
Tissue Specificity Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum
Cellular Localization Endoplasmic reticulum lumen (By similarity).
Database Links
Entrez Gene 8824
Nucleotide Accession NP_003860
Application

Application

CES2 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the CES2 antibody detected the CES2 protein (arrow).

Application

CES2 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CES2 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

CES2 Antibody (Center) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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