Application
Western blot analysis of CREB3L1 Antibody (C-term) in mouse stomach tissue lysates (35ug/lane). CREB3L1 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human prostate carcinoma with CREB3L1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Application
Flow cytometric analysis of hela cells using CREB3L1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | CREB3L1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CREB3L1; OASIS; Cyclic AMP-responsive element-binding protein 3-like protein 1; Old astrocyte specifically-induced substance; Processed cyclic AMP-responsive element-binding protein 3-like protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | OASIS |
|---|---|
| Alternative Names | CREB3L1 OASIS Cyclic AMP-responsive element-binding protein 3-like protein 1 Old astrocyte specifically-induced substance Processed cyclic AMP-responsive element-binding protein 3-like protein 1 |
| Molecular Weight(MW) | 57005 Da |
| Function | Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE (By similarity) |
| Tissue Specificity | Ubiquitously expressed with high levels in pancreas and prostate. Expressed at relatively lower levels in brain |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type II membrane protein |
Application
Western blot analysis of CREB3L1 Antibody (C-term) in mouse stomach tissue lysates (35ug/lane). CREB3L1 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human prostate carcinoma with CREB3L1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
Flow cytometric analysis of hela cells using CREB3L1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
