Application
Western blot analysis of CREB3L1 (arrow) using rabbit polyclonal CREB3L1 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CREB3L1 gene.Application
CREB3L1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CREB3L1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | CREB3L1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CREB3L1; OASIS; Cyclic AMP-responsive element-binding protein 3-like protein 1; Old astrocyte specifically-induced substance; Processed cyclic AMP-responsive element-binding protein 3-like protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | OASIS |
|---|---|
| Alternative Names | CREB3L1 OASIS Cyclic AMP-responsive element-binding protein 3-like protein 1 Old astrocyte specifically-induced substance Processed cyclic AMP-responsive element-binding protein 3-like protein 1 |
| Molecular Weight(MW) | 57005 Da |
| Function | Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE (By similarity) |
| Tissue Specificity | Ubiquitously expressed with high levels in pancreas and prostate. Expressed at relatively lower levels in brain |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type II membrane protein |
| Entrez Gene | 90993 |
|---|---|
| Nucleotide Accession | NP_443086.1 |
Application
Western blot analysis of CREB3L1 (arrow) using rabbit polyclonal CREB3L1 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CREB3L1 gene.
Application
CREB3L1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CREB3L1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
