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CRHR2 Antibody (N-term)

Catalog Number:OM230367
OM230367
Discount Price
OM230367-100ul
1~2 Week
100ul
OM230367-50ul
50ul
OM230367-20ul
20ul
1~2 Week
Product Profile
Product Name CRHR2 Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias CRHR2; CRF2R; CRH2R; Corticotropin-releasing factor receptor 2; Corticotropin-releasing hormone receptor 2
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms CRF2R
CRH2R
Alternative Names CRHR2
CRF2R
CRH2R
Corticotropin-releasing factor receptor 2
Corticotropin-releasing hormone receptor 2
Molecular Weight(MW) 47688 Da
Function This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. Also binds to urocortin I, II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase
Tissue Specificity This CRHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92~121 amino acids from the N-terminal region of human CRHR2.
Cellular Localization Cell membrane; Multi-pass membrane protein.
Database Links
Entrez Gene 1395
Application

Application

Western blot analysis of CRHR2 Antibody (N-term) in NIH-3T3 cell line lysates (35ug/lane). CRHR2 (arrow) was detected using the purified Pab.

Application

CRHR2 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CRHR2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

CRHR2 Antibody (N-term) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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