Application
CRFR2 Antibody (D35) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CRFR2 antibody detected the CRFR2 protein (arrow).Application
CRFR2 Antibody (D35)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CRFR2 Antibody (D35) for immunohistochemistry. Clinical relevance has not been evaluated.Application
CRFR2 Antibody (D35) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | CRFR2 Antibody (D35) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CRHR2; CRF2R; CRH2R; Corticotropin-releasing factor receptor 2; Corticotropin-releasing hormone receptor 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CRF2R CRH2R |
|---|---|
| Alternative Names | CRHR2 CRF2R CRH2R Corticotropin-releasing factor receptor 2 Corticotropin-releasing hormone receptor 2 |
| Molecular Weight(MW) | 47688 Da |
| Function | This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. Also binds to urocortin I, II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase |
| Tissue Specificity | This CRHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-58 amino acids from human CRHR2. |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Entrez Gene | 1395 |
|---|---|
| Nucleotide Accession | NP_001874.2 |
Application
CRFR2 Antibody (D35) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CRFR2 antibody detected the CRFR2 protein (arrow).
Application
CRFR2 Antibody (D35)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CRFR2 Antibody (D35) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
CRFR2 Antibody (D35) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
