Application
Figure 1: Western blot analysis using anti-CRYAB mAb against full-length CRYAB recombinant protein(1).Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human brain hippocampus (A), lung cancer (B), brain tumor (C), breast cance (D), showing cytoplasmic localization with DAB staining using anti-CRYAB mAb.Application
Figure 3: Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissues using anti-CRYAB mAb.| Product Name | CRYAB Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CRYA2; CTPP2; HSPB5; CRYAB |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 1D11C6E6 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500 - 2000. IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CRYA2 |
|---|---|
| Alternative Names | CRYA2 CTPP2 HSPB5 CRYAB |
| Molecular Weight(MW) | 20159 Da |
| Function | May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions |
| Tissue Specificity | Lens as well as other tissues. |
| Cellular Localization | Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles |
| Entrez Gene | 1410 |
|---|---|
| Nucleotide Accession | NP_001876.1 |
Application
Figure 1: Western blot analysis using anti-CRYAB mAb against full-length CRYAB recombinant protein(1).
Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human brain hippocampus (A), lung cancer (B), brain tumor (C), breast cance (D), showing cytoplasmic localization with DAB staining using anti-CRYAB mAb.
Application
Figure 3: Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissues using anti-CRYAB mAb.| Application Notes | WB:1:500 - 2000. IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of CRYAB(aa1-175) expressed in E. Coli. |
