Application
Figure 1: Western blot analysis using CSF1 mouse mAb against human recombinant CSF2 (1) and CSF1 (2).| Product Name | CSF1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MCSF |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 2D10 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500 - 2000. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | MCSF |
|---|---|
| Molecular Weight(MW) | 60179 Da |
| Function | Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration Plays a role in lipoprotein clearance |
| Tissue Specificity | Purified recombinant fragment of human CSF1 expressed in E. Coli. |
| Cellular Localization | Cell membrane; Single-pass membrane protein. |
| Entrez Gene | 1435 |
|---|---|
| Nucleotide Accession | NP_757351.1 |
Application
Figure 1: Western blot analysis using CSF1 mouse mAb against human recombinant CSF2 (1) and CSF1 (2).| Application Notes | WB:1:500 - 2000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human CSF1 expressed in E. Coli. |
