Application
Figure 1: Western blot analysis using anti-CK1 monoclonal antiobdy against truncated CK1 recombinant protein.Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human liver tissue(A), colon carcinoma(B), lung carcinoma(C) and esophagus tissue(D), showing membrane localization using anti-CK1 antibody with DAB staining.| Product Name | CSNK1A1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HLCDGP1; PRO2975; CSNK1A1 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 3C10F7, 3C10G5, PMC01, 4D12B3,3C10F7C11 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500 - 2000. IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | HLCDGP1 PRO2975 CSNK1A1 |
|---|---|
| Molecular Weight(MW) | 38915 Da |
| Function | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45' May play a role in segregating chromosomes during mitosis |
| Tissue Specificity | Purified recombinant fragment of CK1 expressed in E. Coli. |
| Cellular Localization | Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Chromosome, centromere, kinetochore. Nucleus speckle Note=Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis |
| Entrez Gene | 1452 |
|---|---|
| Nucleotide Accession | NP_001883.4 |
Application
Figure 1: Western blot analysis using anti-CK1 monoclonal antiobdy against truncated CK1 recombinant protein.
Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human liver tissue(A), colon carcinoma(B), lung carcinoma(C) and esophagus tissue(D), showing membrane localization using anti-CK1 antibody with DAB staining.| Application Notes | WB:1:500 - 2000. IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of CK1 expressed in E. Coli. |
