Application
CSRP3 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CSRP3 antibody detected the CSRP3 protein (arrow).| Product Name | CSRP3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CSRP3; CLP; MLP; Cysteine and glycine-rich protein 3; Cardiac LIM protein; Cysteine-rich protein 3; LIM domain protein, cardiac; Muscle LIM protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CLP MLP |
|---|---|
| Alternative Names | CSRP3 CLP MLP Cysteine and glycine-rich protein 3 Cardiac LIM protein Cysteine-rich protein 3 LIM domain protein cardiac Muscle LIM protein |
| Molecular Weight(MW) | 20969 Da |
| Function | Positive regulator of myogenesis. Plays a crucial and specific role in the organization of cytosolic structures in cardiomyocytes. Could play a role in mechanical stretch sensing May be a scaffold protein that promotes the assembly of interacting proteins at Z-line structures. It is essential for calcineurin anchorage to the Z line. Required for stress-induced calcineurin-NFAT activation (By similarity) |
| Tissue Specificity | Cardiac and slow-twitch skeletal muscles. |
| Cellular Localization | Nucleus (Potential). Cytoplasm. Cytoplasm, cytoskeleton (Potential). Cytoplasm, myofibril, sarcomere, Z line (By similarity). Note=Mainly cytoplasmic (By similarity). In the nucleus it associates with the actin cytoskeleton (Potential). In the Z line, found associated with GLRX3 (By similarity) |
| Entrez Gene | 8048 |
|---|---|
| Nucleotide Accession | NP_001121128.1 NP_003467.1 |
Application
CSRP3 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CSRP3 antibody detected the CSRP3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
