Application
Figure 1: Western blot analysis using anti-KRT19 monoclonal antibody against truncated KRT19-His recombinant protein(1) and full-length KRT19(aa1-400)-hIgGFc transfected CHO-K1 cell lysate(2).Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma(A), lung cancer(B) and normal colon tissue(C), showing cytoplasmic localization with DAB staining using anti-KRT19 antibody.| Product Name | Cytokeratin 19 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CK19; K1CS; MGC15366; KRT19 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 9H8G6 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500 - 2000. IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CK19 K1CS MGC15366 KRT19 |
|---|---|
| Molecular Weight(MW) | 44106 Da |
| Function | Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle |
| Tissue Specificity | Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin |
| Entrez Gene | 3880 |
|---|---|
| Nucleotide Accession | NP_002267.2 |
Application
Figure 1: Western blot analysis using anti-KRT19 monoclonal antibody against truncated KRT19-His recombinant protein(1) and full-length KRT19(aa1-400)-hIgGFc transfected CHO-K1 cell lysate(2).
Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma(A), lung cancer(B) and normal colon tissue(C), showing cytoplasmic localization with DAB staining using anti-KRT19 antibody.| Application Notes | WB:1:500 - 2000. IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of Cytokeratin 19(aa80-400) expressed in E. Coli. |
