Figure 1: Western blot analysis using KRT19 monoclonal antibody against truncated KRT19-His recombinant protein(1) and full-length KRT19(aa1-400)-hIgGFc transfected CHO-K1 cell lysate(2).
Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle
Tissue Specificity
Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin
Figure 1: Western blot analysis using KRT19 monoclonal antibody against truncated KRT19-His recombinant protein(1) and full-length KRT19(aa1-400)-hIgGFc transfected CHO-K1 cell lysate(2).
Application Notes
WB:1:500 - 2000.
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified recombinant fragment of Cytokeratin 19(aa80-400) expressed in E. Coli strain.