Application
A.Western blot analysis on 15 ng recombinant protein using anti-Keratin 18 RabMAb (Cat. #AJ1223a), dilution 1:1000.Application
B. Immunohistochemical analysis of paraffin-embedded colon carcinoma using anti-Keratin 18 RabMAb (Cat. #AJ1223a).| Product Name | Cytokeratin-18 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KRT18, CYK18, Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein |
| Clonality | Monoclonal |
|---|---|
| Clone Number | E431-1 |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000~5000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CYK18 |
|---|---|
| Alternative Names | KRT18 CYK18 Keratin type I cytoskeletal 18 Cell proliferation-inducing gene 46 protein |
| Molecular Weight(MW) | 48058 Da |
| Function | Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection |
| Tissue Specificity | Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma |
| Cellular Localization | Cytoplasm, perinuclear region. Nucleus, nucleolus |
| Entrez Gene | 3875 |
|---|
Application
A.Western blot analysis on 15 ng recombinant protein using anti-Keratin 18 RabMAb (Cat. #AJ1223a), dilution 1:1000.
Application
B. Immunohistochemical analysis of paraffin-embedded colon carcinoma using anti-Keratin 18 RabMAb (Cat. #AJ1223a).| Application Notes | WB:1:1000~5000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
