CYK18 Antibody (C-term)(Ascites)(Cat. #AM2178a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CYK18 antibody detected the CYK18 protein (arrow).
KRT18; CYK18; Keratin, type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; Keratin-18
Key Feature
Clonality
Monoclonal
Isotype
IgG3
Clone Number
695CT17.2.6
Host Species
Mouse
Tested Applications
WB
WB:1:1000~8000
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CYK18
Alternative Names
KRT18 CYK18 Keratin type I cytoskeletal 18 Cell proliferation-inducing gene 46 protein Cytokeratin-18 Keratin-18
Molecular Weight(MW)
48058 Da
Function
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection
Tissue Specificity
Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma
CYK18 Antibody (C-term)(Ascites)(Cat. #AM2178a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CYK18 antibody detected the CYK18 protein (arrow).
Application Notes
WB:1:1000~8000
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.