Application
Western blot analysis of DCTN2 (arrow) using rabbit polyclonal DCTN2 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DCTN2 gene.Application
DCTN2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DCTN2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | DCTN2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DCTN2; DCTN50; Dynactin subunit 2; 50 kDa dynein-associated polypeptide; Dynactin complex 50 kDa subunit; p50 dynamitin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DCTN50 |
|---|---|
| Alternative Names | DCTN2 DCTN50 Dynactin subunit 2 50 kDa dynein-associated polypeptide Dynactin complex 50 kDa subunit p50 dynamitin |
| Molecular Weight(MW) | 44231 Da |
| Function | Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development |
| Tissue Specificity | This DCTN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the Central region of human DCTN2. |
| Cellular Localization | Cytoplasm, cytoskeleton, centrosome. Membrane; Peripheral membrane protein |
| Entrez Gene | 10540 |
|---|---|
| Nucleotide Accession | NP_006391.1 |
Application
Western blot analysis of DCTN2 (arrow) using rabbit polyclonal DCTN2 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DCTN2 gene.
Application
DCTN2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DCTN2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
