Application
The anti-DRAK2 Pab is used in Western blot to detect DRAK2 in mouse lung tissue lysate.Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.Application
IF staining of Drak2 in WT versus Tg T cells. Permeablized lymph node T cells were double-stained with rabbit anti-Drak2/sheep anti-rabbit Ig-FITC and anti-Thy1.2-PE monoclonal antibody, and signals were registered by confocal microscopy. THE cell surface Thy1.2 is shown in red, and intracellular Drak2 is in green.| Product Name | DRAK2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | STK17B; DRAK2; Serine/threonine-protein kinase 17B; DAP kinase-related apoptosis-inducing protein kinase 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DRAK2 |
|---|---|
| Alternative Names | STK17B DRAK2 Serine/threonine-protein kinase 17B DAP kinase-related apoptosis-inducing protein kinase 2 |
| Molecular Weight(MW) | 42344 Da |
| Function | Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis |
| Tissue Specificity | Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney |
| Cellular Localization | Nucleus. Cell membrane (By similarity). Endoplasmic reticulum-Golgi intermediate compartment (By similarity). Note=Colocalizes with STK17B at the plasma membrane (By similarity) |
| Entrez Gene | 9262 |
|---|
Application
The anti-DRAK2 Pab is used in Western blot to detect DRAK2 in mouse lung tissue lysate.
Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Application
IF staining of Drak2 in WT versus Tg T cells. Permeablized lymph node T cells were double-stained with rabbit anti-Drak2/sheep anti-rabbit Ig-FITC and anti-Thy1.2-PE monoclonal antibody, and signals were registered by confocal microscopy. THE cell surface Thy1.2 is shown in red, and intracellular Drak2 is in green.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
