Application
DSCR2-G27 western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the DSCR2 antibody detected the DSCR2 protein (arrow).| Product Name | DSCR2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PSMG1; C21LRP; DSCR2; PAC1; Proteasome assembly chaperone 1; Chromosome 21 leucine-rich protein; Down syndrome critical region protein 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C21LRP DSCR2 PAC1 |
|---|---|
| Alternative Names | PSMG1 C21LRP DSCR2 PAC1 Proteasome assembly chaperone 1 Chromosome 21 leucine-rich protein Down syndrome critical region protein 2 |
| Molecular Weight(MW) | 32854 Da |
| Function | Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization |
| Tissue Specificity | In the adult, detected in brain, colon, leukocytes, breast and testis. Widely expressed in the fetus. Also expressed in a variety of proliferating cell lines |
| Cellular Localization | Cytoplasm. Endoplasmic reticulum. |
| Entrez Gene | 8624 |
|---|
Application
DSCR2-G27 western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the DSCR2 antibody detected the DSCR2 protein (arrow).| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
