Application
Figure 1: Western blot analysis using anti-Dynamin2 monoclonal antiobdy against truncated Dynamin-2 recombinant protein(1), SKN-SH cell lysate(2) and NIH/3T3 cell lysate(3).Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human cerebrum tissue(left) and myelencephalon tissue(right), showing cytoplasmic localization using anti-Dynamin2 antibody with DAB staining.| Product Name | Dynamin-2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DYN2; DYNII; CMTDI1; CMTDIB; DI-CMTB; DNM2 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 5E4C2F3 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500 - 2000. IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DYN2 |
|---|---|
| Alternative Names | DYN2 DYNII CMTDI1 CMTDIB DI-CMTB DNM2 |
| Molecular Weight(MW) | 98064 Da |
| Function | Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis |
| Tissue Specificity | Ubiquitously expressed. |
| Cellular Localization | Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Midbody. Note=Microtubule- associated. Also found in the postsynaptic density of neuronal cells |
| Entrez Gene | 1785 |
|---|---|
| Nucleotide Accession | NP_004936.2 |
Application
Figure 1: Western blot analysis using anti-Dynamin2 monoclonal antiobdy against truncated Dynamin-2 recombinant protein(1), SKN-SH cell lysate(2) and NIH/3T3 cell lysate(3).
Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human cerebrum tissue(left) and myelencephalon tissue(right), showing cytoplasmic localization using anti-Dynamin2 antibody with DAB staining.| Application Notes | WB:1:500 - 2000. IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of Dynamin-2 expressed in E. Coli. |
