Application
Figure 1: Immunohistochemical analysis of paraffin-embedded human lymph node (left) and colon cancer (right) tissues using anti-eNOS antibody with DAB staining.Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human stomach cancer (left) and ovary cancer (right) tissues using anti-eNOS antibody with DAB staining.| Product Name | eNOS Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ECNOS; NOS3 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 6H2 |
| Host Species | Mouse |
| Tested Applications | IHC |
| IHC:1:200 - 1000. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | ECNOS NOS3 |
|---|---|
| Molecular Weight(MW) | 133289 Da |
| Function | Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets |
| Tissue Specificity | Platelets, placenta, liver and kidney. |
| Cellular Localization | Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity |
| Entrez Gene | 4846 |
|---|---|
| Nucleotide Accession | NP_001153582.1 |
Application
Figure 1: Immunohistochemical analysis of paraffin-embedded human lymph node (left) and colon cancer (right) tissues using anti-eNOS antibody with DAB staining.
Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human stomach cancer (left) and ovary cancer (right) tissues using anti-eNOS antibody with DAB staining.| Application Notes | IHC:1:200 - 1000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human eNOS expressed in E. Coli. |
