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ETS1 Antibody

Catalog Number:OM232524
OM232524
Discount Price
OM232524-100ul
1~2 Week
100ul
OM232524-50ul
50ul
1~2 Week
Product Profile
Product Name ETS1 Antibody
Antibody Type Primary Antibodies
Antigen Alias ETS-1; EWSR2; FLJ10768; ETS1
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 8A8
Host Species Mouse
Tested Applications WBIFFC
WB:1:500 - 2000. IF
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms EWSR2
Alternative Names ETS-1
EWSR2
FLJ10768
ETS1
Molecular Weight(MW) 50408 Da
Function Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells
Tissue Specificity Highly expressed within lymphoid cells. Isoforms c-ETS-1A and Ets-1 p27 are both detected in all fetal tissues tested, but vary with tissue type in adult tissues. None is detected in brain or kidney
Cellular Localization Cytoplasm. Nucleus. Note=Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27
Database Links
Entrez Gene 2113
Nucleotide Accession NP_005229.1
Application

Application

Figure 1: Western blot analysis using ETS1 mouse mAb against Jurkat (1), HepG2 (2)and ETS1-hIgGFc transfected HEK293 (3)cell lysate.

Application

Figure 2:Immunofluorescence analysis of NIH-3T3 cells using anti-ETS1 mAb (green). Blue: DRAQ5 fluorescent DNA dye.

Application

Figure 3: Flow cytometric analysis of Jurkat cells using anti-ETS1 mAb (green) and negative control (purple).
Application Notes WB:1:500 - 2000. IF
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified recombinant fragment of human ETS1 expressed in E. Coli.
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