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F11R Antibody (C-term)

Catalog Number:OM232620
OM232620
Discount Price
OM232620-100ul
1~2 Week
100ul
OM232620-50ul
50ul
OM232620-20ul
20ul
1~2 Week
Product Profile
Product Name F11R Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias F11R; JAM1; JCAM; Junctional adhesion molecule A; Junctional adhesion molecule 1; Platelet F11 receptor; Platelet adhesion molecule 1; CD_antigen=CD321; Flags: Precursor
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBFC
WB:1:100~500 FC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms JAM1
JCAM
Alternative Names F11R
JAM1
JCAM
Junctional adhesion molecule A
Junctional adhesion molecule 1
Platelet F11 receptor
Platelet adhesion molecule 1
CD_antigen=CD321
Flags: Precursor
Molecular Weight(MW) 32583 Da
Function Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus
Tissue Specificity This F11R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253~282 amino acids from the N-term region of human F11R.
Cellular Localization Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein. Note=Localized at tight junctions of both epithelial and endothelial cells
Database Links
Entrez Gene 50848
Application

Application

Western blot analysis of F11R Antibody (C-term) in HepG2 cell line lysates (35ug/lane). F11R (arrow) was detected using the purified Pab.

Application

F11R Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 FC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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