Application
A. Western blot analysis on HeLa cell lysate using anti-JAM1 RabMAb (Cat. #AJ1423b), dilution 1:2000Application
B. Immunohistochemical staining of paraffin-embedded human liver using anti-JAM1 RabMAb (Cat. #AJ1423b).| Product Name | JAM1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | F11R, JAM1, JCAM, Junctional adhesion molecule A, Platelet F11 receptor |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1042Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:2000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | JAM1 JCAM |
|---|---|
| Alternative Names | F11R JAM1 JCAM Junctional adhesion molecule A Platelet F11 receptor |
| Molecular Weight(MW) | 32583 Da |
| Function | Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus |
| Tissue Specificity | A synthetic peptide corresponding to residues near the N-terminus of human JAM1 was used as an immunogen. |
| Cellular Localization | Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein. Note=Localized at tight junctions of both epithelial and endothelial cells |
| Entrez Gene | 50848 |
|---|
Application
A. Western blot analysis on HeLa cell lysate using anti-JAM1 RabMAb (Cat. #AJ1423b), dilution 1:2000
Application
B. Immunohistochemical staining of paraffin-embedded human liver using anti-JAM1 RabMAb (Cat. #AJ1423b).| Application Notes | WB:1:2000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
