Application
Western blot analysis on (A) fetal brain, (B) U937 and (C) SH-SY5Y cell lysates using anti-FKBP12 RabMAb (Cat. #AJ1300a).| Product Name | FKBP12 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR3888 |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:1000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FKBP1 FKBP12 |
|---|---|
| Molecular Weight(MW) | 11951 Da |
| Function | Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides |
| Tissue Specificity | A synthetic peptide corresponding to residues at the C-terminus in human FKBP12 was used as an immunogen. |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 2280 |
|---|
Application
Western blot analysis on (A) fetal brain, (B) U937 and (C) SH-SY5Y cell lysates using anti-FKBP12 RabMAb (Cat. #AJ1300a).| Application Notes | WB:1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
