Application
Western blot analysis of FKBP1A antibody (N-term) (Cat.# AP7756a) in mouse cerebellum tissue lysates, HepG2 and Jurkat cell line lysates (35ug/lane). FKBP1A (arrow) was detected using the purified Pab.Application
FKBP1A Antibody (N-term) (Cat.# AP7756a) IHC analysis in formalin fixed and paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FKBP1A Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
Western blot analysis of FKBP1A (arrow) using rabbit polyclonal FKBP1A Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FKBP1A gene.Application
FKBP1A Antibody (N-term) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | FKBP1A Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FKBP1A; FKBP1; FKBP12; Peptidyl-prolyl cis-trans isomerase FKBP1A; 12 kDa FK506-binding protein; Calstabin-1; FK506-binding protein 1A; Immunophilin FKBP12; Rotamase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FKBP1 FKBP12 |
|---|---|
| Alternative Names | FKBP1A FKBP1 FKBP12 Peptidyl-prolyl cis-trans isomerase FKBP1A 12 kDa FK506-binding protein Calstabin-1 FK506-binding protein 1A Immunophilin FKBP12 Rotamase |
| Molecular Weight(MW) | 11951 Da |
| Function | Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides |
| Tissue Specificity | This FKBP1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human FKBP1A. |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 2280 |
|---|
Application
Western blot analysis of FKBP1A antibody (N-term) (Cat.# AP7756a) in mouse cerebellum tissue lysates, HepG2 and Jurkat cell line lysates (35ug/lane). FKBP1A (arrow) was detected using the purified Pab.
Application
FKBP1A Antibody (N-term) (Cat.# AP7756a) IHC analysis in formalin fixed and paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FKBP1A Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
Western blot analysis of FKBP1A (arrow) using rabbit polyclonal FKBP1A Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FKBP1A gene.
Application
FKBP1A Antibody (N-term) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
