Application
Western blot analysis of FKBP4 Antibody (C-term) in K562 cell line lysates (35ug/lane). FKBP4 (arrow) was detected using the purified Pab.Application
FKBP4 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FKBP4 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
FKBP4 Antibody (C-term) flow cytometric analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.Application
Western blot analysis of FKBP4 (arrow) using rabbit polyclonal FKBP4 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FKBP4 gene.| Product Name | FKBP4 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FKBP4; FKBP52; Peptidyl-prolyl cis-trans isomerase FKBP4; 51 kDa FK506-binding protein; 52 kDa FK506-binding protein; 59 kDa immunophilin; FK506-binding protein 4; FKBP59; HSP-binding immunophilin; Immunophilin FKBP52; Rotamase; Peptidyl-prolyl cis-trans i |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FKBP52 |
|---|---|
| Alternative Names | FKBP4 FKBP52 Peptidyl-prolyl cis-trans isomerase FKBP4 51 kDa FK506-binding protein 52 kDa FK506-binding protein 59 kDa immunophilin FK506-binding protein 4 FKBP59 HSP-binding immunophilin Immunophilin FKBP52 Rotamase Peptidyl-prolyl cis-trans i |
| Molecular Weight(MW) | 51805 Da |
| Function | Immunophilin protein with PPIase and co-chaperone activities (By similarity). Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments (By similarity). The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria |
| Tissue Specificity | Widely expressed. |
| Cellular Localization | Cytoplasm, cytosol (By similarity). Mitochondrion. Nucleus. Cytoplasm, cytoskeleton (By similarity) Note=Shuttles from mitochondria to nucleus; co-localizes in mitochondria with the glucocorticoid receptor |
| Entrez Gene | 2288 |
|---|
Application
Western blot analysis of FKBP4 Antibody (C-term) in K562 cell line lysates (35ug/lane). FKBP4 (arrow) was detected using the purified Pab.
Application
FKBP4 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FKBP4 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
FKBP4 Antibody (C-term) flow cytometric analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application
Western blot analysis of FKBP4 (arrow) using rabbit polyclonal FKBP4 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FKBP4 gene.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
