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FUS Antibody (C-term)

Catalog Number:OM233535
OM233535
Discount Price
OM233535-100ul
1~2 Week
100ul
OM233535-50ul
50ul
OM233535-20ul
20ul
1~2 Week
Product Profile
Product Name FUS Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias FUS; TLS; RNA-binding protein FUS; 75 kDa DNA-pairing protein; Oncogene FUS; Oncogene TLS; POMp75; Translocated in liposarcoma protein
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFCIF
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms TLS
Alternative Names FUS
TLS
RNA-binding protein FUS
75 kDa DNA-pairing protein
Oncogene FUS
Oncogene TLS
POMp75
Translocated in liposarcoma protein
Molecular Weight(MW) 53426 Da
Function Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single- stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity
Tissue Specificity Ubiquitous.
Cellular Localization Nucleus.
Database Links
Entrez Gene 2521
Nucleotide Accession NP_001164105.1
Application

Application

FUS Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (15ug/lane).This demonstrates the FUS antibody detected FUS protein (arrow).

Application

FUS antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FUS antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

FUS Antibody (C-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application

Confocal immunofluorescent analysis of FUS Antibody (C-term)(Cat#AP10187b) with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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