Application
B. Immunohistochemical analysis of paraffin-embedded human tonsils using anti-FYB RabMAb (Cat. #AJ1306b)Application
A. Western blot analysis on TF-1 lysate using anti-FYB RabMAb (Cat. #AJ1306b), 1:10,000 dilution.| Product Name | FYB Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP2546Y |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:250~500 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SLAP130 |
|---|---|
| Alternative Names | FYB SLAP130 FYN-binding protein FYN-T-binding protein FYB-120/130 p120/p130 SLP-76-associated phosphoprotein SLAP-130 Adhesion and degranulation promoting adaptor protein |
| Molecular Weight(MW) | 85387 Da |
| Function | Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton |
| Tissue Specificity | Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues |
| Cellular Localization | Cytoplasm. Nucleus (By similarity). |
| Entrez Gene | 2533 |
|---|
Application
B. Immunohistochemical analysis of paraffin-embedded human tonsils using anti-FYB RabMAb (Cat. #AJ1306b)
Application
A. Western blot analysis on TF-1 lysate using anti-FYB RabMAb (Cat. #AJ1306b), 1:10,000 dilution.| Application Notes | IHC:1:250~500 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
