Application
FYB Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the FYB antibody detected the FYB protein (arrow).| Product Name | FYB Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SLAP130 |
|---|---|
| Alternative Names | FYB SLAP130 FYN-binding protein Adhesion and degranulation promoting adaptor protein FYB-120/130 FYN-T-binding protein SLAP-130 SLP-76-associated phosphoprotein |
| Molecular Weight(MW) | 85387 Da |
| Function | Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton |
| Tissue Specificity | Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues |
| Cellular Localization | Cytoplasm. Nucleus (By similarity). |
| Entrez Gene | 2533 |
|---|---|
| Nucleotide Accession | NP_955367.1 |
Application
FYB Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the FYB antibody detected the FYB protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
