Application
GATM Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GATM antibody detected the GATM protein (arrow).| Product Name | GATM (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | AGAT |
|---|---|
| Alternative Names | GATM AGAT Glycine amidinotransferase mitochondrial L-arginine:glycine amidinotransferase Transamidinase |
| Molecular Weight(MW) | 48455 Da |
| Function | Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis |
| Tissue Specificity | Expressed in brain, heart, kidney, liver, lung, salivary gland and skeletal muscle tissue, with the highest expression in kidney. Biallelically expressed in placenta and fetal tissues |
| Cellular Localization | Isoform 1: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Probably attached to the outer side of the inner membrane |
| Entrez Gene | 2628 |
|---|---|
| Nucleotide Accession | NP_001473.1 |
Application
GATM Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GATM antibody detected the GATM protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
