Application
GATM Antibody (N-term) western blot analysis in HL-60(lane 1),MDA-MB453(lane 2),K562(lane 3) cell line lysates (35ug/lane).This demonstrates the GATM antibody detected the GATM protein (arrow).Application
GATM antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GATM antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | GATM Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | AGAT |
|---|---|
| Alternative Names | GATM AGAT Glycine amidinotransferase mitochondrial L-arginine:glycine amidinotransferase Transamidinase |
| Molecular Weight(MW) | 48455 Da |
| Function | Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis |
| Tissue Specificity | Expressed in brain, heart, kidney, liver, lung, salivary gland and skeletal muscle tissue, with the highest expression in kidney. Biallelically expressed in placenta and fetal tissues |
| Cellular Localization | Isoform 1: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Probably attached to the outer side of the inner membrane |
| Entrez Gene | 2628 |
|---|---|
| Nucleotide Accession | NP_001473.1 |
Application
GATM Antibody (N-term) western blot analysis in HL-60(lane 1),MDA-MB453(lane 2),K562(lane 3) cell line lysates (35ug/lane).This demonstrates the GATM antibody detected the GATM protein (arrow).
Application
GATM antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GATM antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
