Application
GFER Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the GFER antibody detected the GFER protein (arrow).| Product Name | GFER Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ALR, HERV1, HPO |
|---|---|
| Alternative Names | GFER ALR HERV1 HPO FAD-linked sulfhydryl oxidase ALR Augmenter of liver regeneration Hepatopoietin |
| Molecular Weight(MW) | 23449 Da |
| Function | Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re- oxidized by donating electrons to cytochrome c or molecular oxygen |
| Tissue Specificity | Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle |
| Cellular Localization | Isoform 1: Mitochondrion intermembrane space |
Application
GFER Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the GFER antibody detected the GFER protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
