Application
Western blot analysis of GOSR1 Antibody (C-term) in MDA-MB231, NCI-H460, WiDr, CHO cell line lysates (35ug/lane). GOSR1 (arrow) was detected using the purified Pab.| Product Name | GOSR1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GOSR1; GS28; Golgi SNAP receptor complex member 1; 28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GS28 |
|---|---|
| Alternative Names | GOSR1 GS28 Golgi SNAP receptor complex member 1 28 kDa Golgi SNARE protein 28 kDa cis-Golgi SNARE p28 |
| Molecular Weight(MW) | 28613 Da |
| Function | Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi |
| Tissue Specificity | This GOSR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208~238 amino acids from the C-terminal region of human GOSR1. |
| Cellular Localization | Golgi apparatus membrane; Single-pass type IV membrane protein. Note=Enriched on vesicular components at the terminal rims of the Golgi. Found in Golgi microtubules at low temperature (15 degrees Celsius) |
| Entrez Gene | 9527 |
|---|
Application
Western blot analysis of GOSR1 Antibody (C-term) in MDA-MB231, NCI-H460, WiDr, CHO cell line lysates (35ug/lane). GOSR1 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
