Application
GRIA3 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the GRIA3 antibody detected the GRIA3 protein (arrow).| Product Name | GRIA3 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GRIA3; GLUR3; GLURC; Glutamate receptor 3; AMPA-selective glutamate receptor 3; GluR-C; GluR-K3; Glutamate receptor ionotropic, AMPA 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GLUR3 GLURC |
|---|---|
| Alternative Names | GRIA3 GLUR3 GLURC Glutamate receptor 3 AMPA-selective glutamate receptor 3 GluR-C GluR-K3 Glutamate receptor ionotropic AMPA 3 |
| Molecular Weight(MW) | 101157 Da |
| Function | Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate |
| Tissue Specificity | This GRIA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-217 amino acids from the N-terminal region of human GRIA3. |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Note=Interaction with CNIH2 and CNIH3 promotes cell surface expression (By similarity) |
| Entrez Gene | 2892 |
|---|---|
| Nucleotide Accession | NP_015564.4 NP_000819.3 |
Application
GRIA3 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the GRIA3 antibody detected the GRIA3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
