Application
GRIN1 Antibody (Center K412) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GRIN1 antibody detected the GRIN1 protein (arrow).| Product Name | GRIN1 Antibody (Center K412) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GRIN1; NMDAR1; Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NMDAR1 |
|---|---|
| Alternative Names | GRIN1 NMDAR1 Glutamate [NMDA] receptor subunit zeta-1 N-methyl-D-aspartate receptor subunit NR1 |
| Molecular Weight(MW) | 105373 Da |
| Function | NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity) |
| Tissue Specificity | This GRIN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 398-427 amino acids from the Central region of human GRIN1. |
| Cellular Localization | Cell membrane; Multi-pass membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Note=Enriched in postsynaptic plasma membrane and postsynaptic densities (By similarity) |
| Entrez Gene | 2902 |
|---|---|
| Nucleotide Accession | NP_000823.4 |
Application
GRIN1 Antibody (Center K412) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GRIN1 antibody detected the GRIN1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
