Application
GRIN3A Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the GRIN3A antibody detected the GRIN3A protein (arrow).Application
GRIN3A antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GRIN3A antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | GRIN3A Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GRIN3A; KIAA1973; Glutamate [NMDA] receptor subunit 3A; N-methyl-D-aspartate receptor subtype 3A; NMDAR-L |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1973 |
|---|---|
| Alternative Names | GRIN3A KIAA1973 Glutamate [NMDA] receptor subunit 3A N-methyl-D-aspartate receptor subtype 3A NMDAR-L |
| Molecular Weight(MW) | 125465 Da |
| Function | NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. May play a role in the development of dendritic spines May play a role in PPP2CB-NMDAR mediated signaling mechanism (By similarity) |
| Tissue Specificity | This GRIN3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1087-1115 amino acids from the C-terminal region of human GRIN3A. |
| Cellular Localization | Cell membrane; Multi-pass membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Note=Enriched in postsynaptic plasma membrane and postsynaptic densities Requires the presence of GRIN1 to be targeted at the plasma membrane (By similarity) |
| Entrez Gene | 116443 |
|---|---|
| Nucleotide Accession | NP_597702.2 |
Application
GRIN3A Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the GRIN3A antibody detected the GRIN3A protein (arrow).
Application
GRIN3A antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GRIN3A antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
