Application
GRIN3A Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the GRIN3A antibody detected the GRIN3A protein (arrow).Application
GRIN3A Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the GRIN3A antibody detected the GRIN3A protein (arrow).Application
GRIN3A Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GRIN3A Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | GRIN3A Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GRIN3A; KIAA1973; Glutamate [NMDA] receptor subunit 3A; N-methyl-D-aspartate receptor subtype 3A; NMDAR-L |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1973 |
|---|---|
| Alternative Names | GRIN3A KIAA1973 Glutamate [NMDA] receptor subunit 3A N-methyl-D-aspartate receptor subtype 3A NMDAR-L |
| Molecular Weight(MW) | 125465 Da |
| Function | NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. May play a role in the development of dendritic spines May play a role in PPP2CB-NMDAR mediated signaling mechanism (By similarity) |
| Tissue Specificity | This GRIN3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 782-812 amino acids from the C-terminal region of human GRIN3A. |
| Cellular Localization | Cell membrane; Multi-pass membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Note=Enriched in postsynaptic plasma membrane and postsynaptic densities Requires the presence of GRIN1 to be targeted at the plasma membrane (By similarity) |
| Entrez Gene | 116443 |
|---|---|
| Nucleotide Accession | NP_597702.2 |
Application
GRIN3A Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the GRIN3A antibody detected the GRIN3A protein (arrow).
Application
GRIN3A Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the GRIN3A antibody detected the GRIN3A protein (arrow).
Application
GRIN3A Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GRIN3A Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
