Application
GSN Antibody (N-term) (Cat. #AM1936b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the GSN antibody detected the GSN protein (arrow).| Product Name | GSN Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GSN; Gelsolin; AGEL; Actin-depolymerizing factor; Brevin |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Clone Number | 328CT2.2.1 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GSN Gelsolin AGEL Actin-depolymerizing factor Brevin |
|---|---|
| Molecular Weight(MW) | 85698 Da |
| Function | Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis |
| Tissue Specificity | Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells |
| Cellular Localization | Isoform 2: Cytoplasm, cytoskeleton. |
| Entrez Gene | 2934 |
|---|---|
| Nucleotide Accession | NP_000168.1 |
Application
GSN Antibody (N-term) (Cat. #AM1936b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the GSN antibody detected the GSN protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS. |
