HIST1H2BJ/HIST1H2BK/HIST3H2BB Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the HIST1H2BJ/HIST1H2BK/HIST3H2BB antibody detected the HIST1H2BJ/HIST1H2BK/HIST3H2BB protein (arrow).
HIST1H2BJ H2BFR Histone H2B type 1-J Histone H2B.1 Histone H2B.r
Molecular Weight(MW)
13904 Da
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Tissue Specificity
This HIST1H2BJ/HIST1H2BK/HIST3H2BB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-136 amino acids from the C-terminal region of human HIST1H2BJ/HIST1H2BK/HIST3H2BB.
HIST1H2BJ/HIST1H2BK/HIST3H2BB Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the HIST1H2BJ/HIST1H2BK/HIST3H2BB antibody detected the HIST1H2BJ/HIST1H2BK/HIST3H2BB protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.