Application
HOPX Antibody (C-term) western blot analysis in Ramos,A2058,293 cell line lysates (35ug/lane).This demonstrates the HOPX antibody detected the HOPX protein (arrow).Application
HOPX Antibody (C-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | HOPX Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HOPX; HOD; HOP; LAGY; NECC1; OB1; Homeodomain-only protein; Lung cancer-associated Y protein; Not expressed in choriocarcinoma protein 1; Odd homeobox protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HOD HOP LAGY NECC1 OB1 |
|---|---|
| Alternative Names | HOPX HOD HOP LAGY NECC1 OB1 Homeodomain-only protein Lung cancer-associated Y protein Not expressed in choriocarcinoma protein 1 Odd homeobox protein 1 |
| Molecular Weight(MW) | 8260 Da |
| Function | Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor |
| Tissue Specificity | Widely expressed. Expressed in the heart, brain, placenta, lung, skeletal and smooth muscles, uterus, urinary bladder, kidney and spleen. Down-regulated in some types of cancer such as lung cancer, choriocarcinoma, head and neck squamous cell carcinoma and oral squamous cell carcinoma |
| Cellular Localization | Nucleus (By similarity). |
| Entrez Gene | 84525 |
|---|---|
| Nucleotide Accession | NP_001138931.1 NP_631957.1 NP_115884.4 |
Application
HOPX Antibody (C-term) western blot analysis in Ramos,A2058,293 cell line lysates (35ug/lane).This demonstrates the HOPX antibody detected the HOPX protein (arrow).
Application
HOPX Antibody (C-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
